SCHEMBL23601688

SCHEMBL23601688

CN/N=C/N(C)c1cccc(-c2ccc(C3(C#N)CC3)nc2)c1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NR1H4 Q96RI1 3/20 0.33
FFAR4 Q5NUL3 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23601692 0.74 AR (0.39) FFAR4
SCHEMBL24721009 0.71 RXRA (0.39) FFAR4
SCHEMBL23601698 0.69 CHRNB4 (0.38)
SCHEMBL24721520 0.67 RXRA (0.37) FFAR4
SCHEMBL22663451 0.63 CSF1R (0.45) FFAR4
SCHEMBL12918279 0.60 OPRM1 (0.40) FFAR4
SCHEMBL876202 0.60 MAP3K12 (0.50)
SCHEMBL21246199 0.58 OPRM1 (0.39) FFAR4
SCHEMBL1760004 0.58 FFAR4 (0.43) FFAR4
SCHEMBL24867933 0.58 TRPV4 (0.34) FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021130638-A1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS CARNA BIOSCIENCES, INC. (JP) 2021-07-01 WO disclosed