Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GPR88 | Q9GZN0 | 3/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | GAK | O14976 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24721057 | 0.85 | PTPN5 (0.43) | HSD17B1HSD17B2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL13680445 | 0.80 | HSD17B1 (0.46) | HSD17B1HSD17B2KDRARPTPN5 | |
| SCHEMBL23601700 | 0.78 | L3MBTL1 (0.44) | HSD17B1HSD17B2KDRARALDH1A1 | |
| SCHEMBL23600940 | 0.78 | CCR1 (0.38) | CYP11B1GRIN2BGPR88ALDH1A1GABRA5 | |
| SCHEMBL12498936 | 0.76 | HSD17B1 (0.67) | HSD17B1HSD17B2KDRPIK3CDPIK3CA | |
| SCHEMBL23601917 | 0.74 | PIK3CD (0.50) | HSD17B1HSD17B2KDRPIK3CDPIK3CA | |
| SCHEMBL13036072 | 0.72 | AR (0.48) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL29499578 | 0.71 | LIPE (0.36) | CYP11B1GPR88ALDH1A1GABRA5 | |
| SCHEMBL24946129 | 0.71 | FEN1 (0.41) | PIK3CDPIK3CAPIK3CBPIK3CGGPR88 | |
| SCHEMBL23116240 | 0.70 | GPR88 (0.39) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |