Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | ALPL | P05186 | 3/20 | 0.35 |
| ▸ | ALPI | P09923 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALPG | P10696 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23718641 | 0.78 | KDM4E (0.43) | LMNAHSD17B10KDM4ESMN1; SMN2HTT | |
| SCHEMBL23008292 | 0.78 | HTR2A (0.42) | HTR2AHTR2CHTR2BESR1ESR2 | |
| SCHEMBL20178503 | 0.77 | LMNA (0.53) | LMNAHSD17B10KDM4ESMN1; SMN2HTT | |
| SCHEMBL23939714 | 0.76 | HTR2A (0.40) | HTR2AHTR2CHTR2BCYP2D6CYP3A4 | |
| SCHEMBL19132613 | 0.74 | KDM4E (0.48) | LMNAHSD17B10KDM4ESMN1; SMN2HTT | |
| SCHEMBL20354295 | 0.73 | HTR2A (0.37) | HTR2AHTR2CHTR2BKMT2AMEN1 | |
| SCHEMBL3268547 | 0.72 | HSD17B10 (0.54) | LMNAHSD17B10KDM4EHTTALDH1A1 | |
| SCHEMBL21497378 | 0.71 | HTR2A (0.43) | HTR2AHTR2CHTR2BCYP2D6CYP3A4 | |
| SCHEMBL12545719 | 0.71 | HSD17B10 (0.53) | LMNAHSD17B10KDM4ESMN1; SMN2HTT | |
| SCHEMBL5029652 | 0.71 | HSD17B10 (0.53) | LMNAHSD17B10KDM4EHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210198263-A1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS, INC. (US) | 2021-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210198263-A1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | USP30, UCHL1, ADRM1 | LMNA 2824/4885HSD17B10 793/4885KDM4E 2992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.