Sugi Predict

Sugi Predict / Compounds / SCHEMBL2360748

SCHEMBL2360748

SCHEMBL2360748

Cc1ccc2nc(N)[nH]c2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PLAU P00749 1/20 0.61
▸ HTR3E A5X5Y0 1/20 0.61
▸ HTR3B O95264 1/20 0.61
▸ HTR3A P46098 1/20 0.61
▸ BACE1 P56817 1/20 0.61
▸ HTR3D Q70Z44 1/20 0.61
▸ HTR3C Q8WXA8 1/20 0.61
▸ FABP6 P51161 1/20 0.60
▸ KMT2A Q03164 4/20 0.58
▸ POLB P06746 2/20 0.58
▸ ALDH1A1 P00352 6/20 0.57
▸ NPC1 O15118 4/20 0.57
▸ RAB9A P51151 4/20 0.57
▸ KDM4E B2RXH2 3/20 0.57
▸ MAPT P10636 3/20 0.57
▸ GAA P10253 3/20 0.57
▸ SMN1; SMN2 Q16637 2/20 0.57
▸ TYMS P04818 1/20 0.57
▸ HPGD P15428 3/20 0.56
▸ USP2 O75604 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21023423 0.87 NPC1 (0.68) KMT2APOLBALDH1A1NPC1RAB9A
SCHEMBL129665 0.84 FABP6 (0.60) PLAUHTR3EHTR3BHTR3ABACE1
SCHEMBL2780693 0.80 KMT2A (0.58) KMT2APOLBALDH1A1NPC1RAB9A
SCHEMBL29727934 0.79 ALDH1A1 (0.66) KMT2APOLBALDH1A1NPC1RAB9A
SCHEMBL266609 0.79 ALDH1A1 (0.66) KMT2APOLBALDH1A1NPC1RAB9A
SCHEMBL725354 0.79 PLAU (0.66) PLAUHTR3EHTR3BHTR3ABACE1
Hydrochloric Acid SCHEMBL6621844 0.78 PLAU (0.63) PLAUHTR3EHTR3BHTR3ABACE1
SCHEMBL726013 0.76 PLAU (1.00) PLAUHTR3EHTR3BHTR3ABACE1
SCHEMBL9305169 0.76 KMT2A (0.58) KMT2APOLBALDH1A1NPC1RAB9A
SCHEMBL21983779 0.76 PLAU (0.61) PLAUHTR3EHTR3BHTR3ABACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10292390-B2 Inhibition and dispersion of bacterial biofilms with 2-aminobenzimidazole derivatives WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2019-05-21 — — US claimed
US-20130136782-A1 Inhibition and Dispersion of Bacterial Biofilms with 2-Aminobenzimidazole Derivatives WISCONSIN ALUMNI RESEARCH FOUNDATION 2013-05-30 — — US claimed
US-4496727-A ORGANIC PIGMENTS; PLASTICS; LACQUERS; INKS; COATINGS; COLOR FASTNESS CIBA-GEIGY CORPORATION (US) 1985-01-29 — — US claimed
US-4385174-A FOR PIGMENTS CIBA-GEIGY CORPORATION (US) 1983-05-24 — — US claimed
US-4349671-A Process for the production of metal complexes of isoindoline azines CIBA-GEIGY CORPORATION (US) 1982-09-14 — — US claimed
US-12030853-B2 MASP-2 inhibitors and methods of use OMEROS CORPORATION (US) 2024-07-09 — — US disclosed
CN-114574988-B Preparation method of flame-retardant polyamide 6 fiber based on phosphorus-nitrogen synergistic flame retardant 东华大学 2024-01-30 — — CN disclosed
CN-114437129-B Phosphorus-nitrogen synergistic flame retardant, flame-retardant nylon 6 resin and preparation method thereof 东华大学 2024-01-30 — — CN disclosed
CN-114989096-B Thioazole compound and preparation method and application thereof 赣南师范大学 2023-10-24 — — CN disclosed
CN-114989096-A Thioazole compound and preparation method and application thereof 赣南师范大学 2022-09-02 — — CN disclosed
CN-114574988-A Preparation method of flame-retardant polyamide 6 fiber based on phosphorus-nitrogen synergistic flame retardant 东华大学 2022-06-03 — — CN disclosed
CN-114437129-A Phosphorus-nitrogen synergistic flame retardant, flame-retardant nylon 6 resin and preparation method thereof 东华大学 2022-05-06 — — CN disclosed
US-4237293-A COLORFAST SHADES OF YELLOW TO RED FOR PLASTICS AND LACQUERS CIBA-GEIGY CORPORATION (US) 1980-12-02 — — US disclosed
US-4136189-A 2-(5-NITRO-FURFURYLIDENE)-AMINO-BENZIMIDOLES AND FUNGICIDAL COMPOSITIONS CONTAINING THE SAME CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) 1979-01-23 — — US disclosed
US-4132708-A Metal complexes of azomethines and process for their manufacture CIBA-GEIGY CORPORATION (US) 1979-01-02 — — US disclosed
US-4111947-A DYES, PLASTICS, LACQUERS CIBA-GEIGY CORPORATION (US) 1978-09-05 — — US disclosed
US-4022770-A COLORING CIBA-GEIGY CORPORATION (US) 1977-05-10 — — US disclosed
US-4006127-A Cationic diazacyanine dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1977-02-01 — — US disclosed
US-4000275-A BENZIMIDAZO(2,1-B) QUINAZOLIN-12(6H)ONES ELI LILLY AND COMPANY (US) 1976-12-28 — — US disclosed
US-3933846-A FUNGICIDES, OVICIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-01-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130136782-A1 Inhibition and Dispersion of Bacterial Biofilms with 2-Aminobenzimidazole Derivatives FLNB, BRI3BP, CCNI PLAU 1451/4885HTR3E 1093/4885HTR3B 930/4885
US-10292390-B2 Inhibition and dispersion of bacterial biofilms with 2-aminobenzimidazole derivatives FLNB, BRI3BP, CCNI PLAU 1451/4885HTR3E 1093/4885HTR3B 930/4885
US-12030853-B2 MASP-2 inhibitors and methods of use MASP2, METAP2, SPINT2 PLAU 303/4885HTR3E 3746/4885HTR3B 3778/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.