Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 6/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.44 |
| ▸ | PTGES | O14684 | 7/20 | 0.41 |
| ▸ | RHEB | Q15382 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2361888 | 0.80 | AMY1A (0.47) | AMY1ADGAT1PTGESJAK2PDE7A | |
| SCHEMBL2362277 | 0.79 | PLAU (0.51) | AMY1ADGAT1 | |
| SCHEMBL2360991 | 0.77 | RHEB (0.52) | DGAT1PTGESRHEBJAK2 | |
| SCHEMBL2361306 | 0.76 | AMY1A (0.44) | AMY1ADGAT1PTGESPDE7AORAI1 | |
| SCHEMBL1512040 | 0.74 | IDH1 (0.41) | SRC | |
| SCHEMBL2361250 | 0.74 | AMY1A (0.43) | AMY1ADGAT1PTGESJAK2PDE7A | |
| SCHEMBL13405914 | 0.74 | RHEB (0.54) | AMY1ADGAT1PTGESRHEBJAK2 | |
| SCHEMBL2361475 | 0.74 | DGAT1 (0.43) | AMY1ADGAT1PTGESPDE7AORAI1 | |
| SCHEMBL2361209 | 0.73 | PTGES (0.43) | AMY1ADGAT1PTGESPDE7AORAI1 | |
| SCHEMBL2361234 | 0.73 | PTGES (0.45) | AMY1ADGAT1PTGESPDE7AORAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011099832-A2 | NOVEL BENZIMIDAZOLE COMPOUND, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CRYSTALGENOMICS, INC. (KR) | 2011-08-18 | — | — | WO | disclosed |
| WO-2011099832-A2 | NOVEL BENZIMIDAZOLE COMPOUND, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CRYSTALGENOMICS, INC. (KR) | 2011-08-18 | — | — | WO | disclosed |