Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 17/20 | 0.51 |
| ▸ | PLG | P00747 | 16/20 | 0.51 |
| ▸ | F10 | P00742 | 15/20 | 0.48 |
| ▸ | F2 | P00734 | 13/20 | 0.48 |
| ▸ | PLAT | P00750 | 11/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.44 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2361888 | 0.79 | AMY1A (0.47) | AMY1ADGAT1 | |
| SCHEMBL2361085 | 0.79 | AMY1A (0.44) | AMY1ADGAT1 | |
| SCHEMBL2361762 | 0.78 | F10 (0.54) | PLAUPLGF10F2PLAT | |
| SCHEMBL2361306 | 0.74 | AMY1A (0.44) | AMY1ADGAT1 | |
| SCHEMBL2361250 | 0.73 | AMY1A (0.43) | AMY1ADGAT1 | |
| SCHEMBL2361706 | 0.73 | PTGES (0.48) | — | |
| SCHEMBL13405914 | 0.73 | RHEB (0.54) | AMY1ADGAT1 | |
| SCHEMBL2361475 | 0.72 | DGAT1 (0.43) | AMY1ADGAT1 | |
| SCHEMBL2361234 | 0.71 | PTGES (0.45) | AMY1ADGAT1 | |
| SCHEMBL2362184 | 0.71 | AMY1A (0.42) | AMY1ADGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011099832-A2 | NOVEL BENZIMIDAZOLE COMPOUND, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CRYSTALGENOMICS, INC. (KR) | 2011-08-18 | — | — | WO | disclosed |