Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.60 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.60 |
| ▸ | TLR2 | O60603 | 1/20 | 0.47 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.46 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.46 |
| ▸ | NMT2 | O60551 | 2/20 | 0.45 |
| ▸ | NMT1 | P30419 | 2/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.44 |
| ▸ | CPB1 | P15086 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.43 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.42 |
| ▸ | CHRNG | P07510 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23610946 | 0.93 | SIRT1 (0.57) | SIRT1SIRT6TLR2GNAI3GNAO1 | |
| SCHEMBL19839612 | 0.88 | SIRT1 (0.80) | SIRT1SIRT6TLR2GNAI3GNAO1 | |
| SCHEMBL19839611 | 0.88 | SIRT1 (0.80) | SIRT1SIRT6TLR2GNAI3GNAO1 | |
| SCHEMBL25386549 | 0.81 | SIRT1 (0.49) | SIRT1SIRT6TLR2GRIN1GRIN2A | |
| SCHEMBL19839576 | 0.81 | SIRT1 (0.69) | SIRT1SIRT6TLR2GNAI3GNAO1 | |
| SCHEMBL19839581 | 0.81 | SIRT1 (0.69) | SIRT1SIRT6TLR2GNAI3GNAO1 | |
| SCHEMBL19839579 | 0.81 | SIRT1 (0.69) | SIRT1SIRT6TLR2GNAI3GNAO1 | |
| Hydrochloric Acid SCHEMBL19839873 | 0.80 | SIRT1 (0.67) | SIRT1SIRT6TLR2GNAI3GNAO1 | |
| Hydrochloric Acid SCHEMBL19839877 | 0.80 | SIRT1 (0.67) | SIRT1SIRT6TLR2GNAI3GNAO1 | |
| SCHEMBL20705144 | 0.79 | MMP1 (0.45) | SIRT1SIRT6NMT2NMT1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11655210-B2 | Compound for improving L-arginine bioavailability | THE GENERAL HOSPITAL CORPORATION (US) | 2023-05-23 | — | — | US | disclosed |
| US-20210206717-A1 | Compound for Improving L-Arginine Bioavailability | THE GENERAL HOSPITAL CORPORATION | 2021-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210206717-A1 | Compound for Improving L-Arginine Bioavailability | ARG1, ARG2, NOS2 | SIRT1 84/4885SIRT6 117/4885TLR2 4242/4885 |
| US-11655210-B2 | Compound for improving L-arginine bioavailability | ARG1, ARG2, NOS2 | SIRT1 84/4885SIRT6 117/4885TLR2 4242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.