Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 2/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23616929 | 0.84 | TBXAS1 (0.43) | MAPK1L3MBTL1TBXAS1PKM | |
| SCHEMBL21455476 | 0.75 | MAPT (0.35) | MAPK1L3MBTL1TBXAS1PKMPOLB | |
| SCHEMBL30011105 | 0.74 | DPP4 (0.46) | DRD2 | |
| SCHEMBL21437959 | 0.74 | DPP4 (0.46) | DRD2 | |
| SCHEMBL23617355 | 0.73 | PDCD1 (0.38) | ALOX15TBXAS1PKMEGFR | |
| SCHEMBL21455445 | 0.72 | PKM (0.40) | L3MBTL1CYP4Z1TBXAS1PKMEGFR | |
| SCHEMBL23617025 | 0.72 | MAPT (0.39) | L3MBTL1TBXAS1POLBEGFR | |
| SCHEMBL23617054 | 0.72 | BACE1 (0.38) | L3MBTL1 | |
| SCHEMBL21455194 | 0.71 | TBXAS1 (0.45) | MAPK1L3MBTL1TBXAS1PKM | |
| SCHEMBL23616975 | 0.71 | ALDH1A1 (0.36) | L3MBTL1TBXAS1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3687506-B1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | BIOCRYST PHARM INC (US) | 2021-07-07 | — | — | EP | disclosed |