Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | HBB | P68871 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11857136 | 0.87 | MAPT (0.59) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL30702212 | 0.85 | MAPT (0.56) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL3948845 | 0.85 | MAPT (0.56) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL8154396 | 0.83 | KMT2A (0.56) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL29458361 | 0.83 | HSD17B10 (0.60) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL599658 | 0.83 | HSD17B10 (0.60) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL5311960 | 0.80 | KMT2A (0.55) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL856747 | 0.80 | ACHE (0.56) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| Benzamide SCHEMBL3076280 | 0.80 | MAPT (0.52) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL11861705 | 0.80 | L3MBTL1 (0.55) | MAPTKDM4EMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11795132-B2 | Application of metal hydride/palladium compound system in preparation of 1,3-dicarbonyl compound in cascade reaction of electron-deficient alkene compound | SOOCHOW UNIVERSITY (CN) | 2023-10-24 | — | — | US | disclosed |
| US-11795132-B2 | Application of metal hydride/palladium compound system in preparation of 1,3-dicarbonyl compound in cascade reaction of electron-deficient alkene compound | SOOCHOW UNIVERSITY (CN) | 2023-10-24 | — | — | US | disclosed |
| US-11180437-B2 | Method for preparing 1,3-dicarbonyl compound based on metal hydride/palladium compound system | SOOCHOW UNIVERSITY (CN) | 2021-11-23 | — | — | US | disclosed |
| US-20210206708-A1 | METHOD FOR PREPARING 1,3-DICARBONYL COMPOUND BASED ON METAL HYDRIDE/PALLADIUM COMPOUND SYSTEM | SOOCHOW UNIVERSITY (CN) | 2021-07-08 | — | — | US | disclosed |
| US-20210206707-A1 | APPLICATION OF METAL HYDRIDE/PALLADIUM COMPOUND SYSTEM IN PREPARATION OF 1,3-DICARBONYL COMPOUND IN CASCADE REACTION OF ELECTRON-DEFICIENT ALKENE COMPOUND | SOOCHOW UNIVERSITY (CN) | 2021-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210206708-A1 | METHOD FOR PREPARING 1,3-DICARBONYL COMPOUND BASED ON METAL HYDRIDE/PALLADIUM COMPOUND SYSTEM | ODC1, HVCN1, PDCD1 | MAPT 3798/4885KDM4E 1311/4885MEN1 1294/4885 |
| US-11180437-B2 | Method for preparing 1,3-dicarbonyl compound based on metal hydride/palladium compound system | ODC1, HVCN1, PDCD1 | MAPT 3798/4885KDM4E 1311/4885MEN1 1294/4885 |
| US-20210206707-A1 | APPLICATION OF METAL HYDRIDE/PALLADIUM COMPOUND SYSTEM IN PREPARATION OF 1,3-DICARBONYL COMPOUND IN CASCADE REACTION OF ELECTRON-DEFICIENT ALKENE COMPOUND | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HVCN1, HRH4 | MAPT 4337/4885KDM4E 924/4885MEN1 1285/4885 |
| US-11795132-B2 | Application of metal hydride/palladium compound system in preparation of 1,3-dicarbonyl compound in cascade reaction of electron-deficient alkene compound | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HVCN1, HRH4 | MAPT 4337/4885KDM4E 924/4885MEN1 1285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.