Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 2/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23619016 | 0.92 | ROCK2 (0.44) | ROCK2RORCPPARGDRD2 | |
| SCHEMBL28623367 | 0.80 | HTR7 (0.43) | HTR7CCR2SERPINE1 | |
| SCHEMBL28627879 | 0.79 | LMNA (0.42) | — | |
| SCHEMBL23619064 | 0.75 | MAPT (0.43) | DDR1RORC | |
| SCHEMBL23619005 | 0.75 | ROCK2 (0.45) | ROCK2PPARGDRD2 | |
| SCHEMBL23619025 | 0.73 | ROCK2 (0.45) | ROCK2PPARGDRD2 | |
| SCHEMBL23619113 | 0.73 | ROCK2 (0.45) | ROCK2RORCPPARGDRD2 | |
| SCHEMBL23618986 | 0.72 | RORC (0.37) | RORC | |
| SCHEMBL28626446 | 0.72 | RORC (0.37) | RORC | |
| SCHEMBL23619094 | 0.72 | ROCK2 (0.44) | ROCK2PPARGDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021136339-A1 | AMIDE COMPOUND WITH BICYCLIC STRUCTURE AND USE THEREOF IN DRUG | 广东东阳光药业有限公司 | 2021-07-08 | — | — | WO | disclosed |