Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | PHGDH | O43175 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 2/20 | 0.40 |
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GUSB | P08236 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28623367 | 0.89 | HTR7 (0.43) | LMNAIDH1ACACBKMT2AMEN1 | |
| SCHEMBL28629894 | 0.89 | IDH1 (0.38) | LMNAIDH1 | |
| SCHEMBL23618989 | 0.79 | ROCK2 (0.40) | — | |
| SCHEMBL28618410 | 0.78 | TEAD1 (0.39) | IDH1KMT2AMEN1MAPT | |
| SCHEMBL28626446 | 0.75 | RORC (0.37) | ACACBNPSR1 | |
| SCHEMBL23618986 | 0.75 | RORC (0.37) | ACACBNPSR1 | |
| SCHEMBL17991562 | 0.74 | PHGDH (0.41) | LMNAPHGDHCACNA1BKMT2AMEN1 | |
| SCHEMBL29501141 | 0.74 | PHGDH (0.41) | LMNAPHGDHCACNA1BKMT2AMEN1 | |
| SCHEMBL5854429 | 0.74 | P2RX3 (0.50) | IDH1TP53 | |
| SCHEMBL5854432 | 0.74 | P2RX3 (0.50) | IDH1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121463-A | Amide compound with bicyclic structure and application thereof in medicines | 广东东阳光药业有限公司 | 2021-07-16 | — | — | CN | disclosed |