Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23619688 | 0.83 | ALDH1A1 (0.69) | ALDH1A1HPGDPOLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL25144291 | 0.78 | ANO1 (0.60) | HPGDSMN1; SMN2KMT2ALMNAANO1 | |
| SCHEMBL24713218 | 0.77 | CA2 (0.48) | ALDH1A1HPGDSMN1; SMN2KMT2AANO1 | |
| SCHEMBL11280611 | 0.76 | AKR1B1 (0.52) | ALDH1A1SMN1; SMN2KMT2ALMNAANO1 | |
| SCHEMBL8744794 | 0.76 | AKR1B1 (0.53) | ALDH1A1HPGDPOLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL8744800 | 0.76 | AKR1B1 (0.53) | ALDH1A1HPGDPOLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL25144288 | 0.76 | HPGD (0.50) | ALDH1A1HPGDPOLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL23619805 | 0.76 | SMN1; SMN2 (0.66) | ALDH1A1HPGDPOLBSMN1; SMN2KMT2A | |
| SCHEMBL8744811 | 0.74 | SDCBP (0.51) | ALDH1A1HPGDPOLBSMN1; SMN2KMT2A | |
| SCHEMBL8744816 | 0.74 | SDCBP (0.51) | ALDH1A1HPGDPOLBSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021136238-A1 | FUSED RING COMPOUND AND APPLICATION THEREOF | 武汉朗来科技发展有限公司 | 2021-07-08 | — | — | WO | disclosed |