Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 8/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 8/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.46 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20595513 | 0.84 | CYP1A2 (0.48) | CYP1A1CYP1B1CYP1A2NFE2L2NCF1 | |
| SCHEMBL28472704 | 0.82 | CYP1A2 (0.52) | CYP1A1CYP1B1CYP1A2NFE2L2TUBB1 | |
| SCHEMBL19766709 | 0.82 | CYP1A2 (0.52) | CYP1A1CYP1B1CYP1A2NFE2L2TUBB1 | |
| SCHEMBL17821561 | 0.81 | CYP1A2 (0.50) | CYP1A1CYP1B1CYP1A2NFE2L2TUBB1 | |
| SCHEMBL17821560 | 0.81 | CYP1A2 (0.50) | CYP1A1CYP1B1CYP1A2NFE2L2TUBB1 | |
| SCHEMBL14820093 | 0.78 | CYP1A2 (0.52) | CYP1A1CYP1B1CYP1A2NFE2L2ALDH1A1 | |
| SCHEMBL17106543 | 0.78 | CYP1A2 (0.52) | CYP1A1CYP1B1CYP1A2NFE2L2ALDH1A1 | |
| SCHEMBL17106542 | 0.78 | CYP1A2 (0.52) | CYP1A1CYP1B1CYP1A2NFE2L2ALDH1A1 | |
| SCHEMBL20227828 | 0.78 | MAPT (0.54) | ALDH1A1KDM4EMEN1MAPTHPGD | |
| SCHEMBL13344127 | 0.77 | CYP1A2 (0.46) | CYP1A1CYP1B1CYP1A2NFE2L2TUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11939319-B2 | Pyridinyl and pyrazinyl-(asa)indolsulfonamides | UCB PHARMA GMBH (DE) | 2024-03-26 | — | — | US | disclosed |
| US-20230202985-A1 | Indoles, Indazoles, and Related Analogs for Inhibiting YAP/TAZ-TEAD | CISTIM LEUVEN VZW (BE) | 2023-06-29 | — | — | US | disclosed |
| US-20210206749-A1 | Pyridinyl and Pyrazinyl-(Asa)Indolsulfonamides | UCB PHARMA GMBH (DE) | 2021-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230202985-A1 | Indoles, Indazoles, and Related Analogs for Inhibiting YAP/TAZ-TEAD | YAP1, TEAD2, TEAD3 | CYP1A1 3122/4885CYP1B1 2673/4885CYP1A2 2887/4885 |
| US-20210206749-A1 | Pyridinyl and Pyrazinyl-(Asa)Indolsulfonamides | GPR17, GPR18, GPR119 | CYP1A1 1488/4885CYP1B1 1406/4885CYP1A2 1013/4885 |
| US-11939319-B2 | Pyridinyl and pyrazinyl-(asa)indolsulfonamides | GPR17, GPR18, GPR119 | CYP1A1 1488/4885CYP1B1 1406/4885CYP1A2 1013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.