Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2362286 | 0.82 | TLR8 (0.60) | LMNAMAPTTSHRCREBBPHSD17B10 | |
| SCHEMBL18731439 | 0.76 | LMNA (0.61) | LMNAMAPTTSHRCREBBPSMN1; SMN2 | |
| SCHEMBL2853106 | 0.74 | ACSS2 (0.43) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL23638275 | 0.72 | RAB9A (0.58) | LMNAMAPTTSHRCREBBPSMN1; SMN2 | |
| SCHEMBL18731438 | 0.71 | LMNA (0.53) | LMNAMAPTTSHRCREBBPMEN1 | |
| SCHEMBL6414028 | 0.70 | JAK2 (0.47) | MAPTSMN1; SMN2HSD17B10CASP1MEN1 | |
| SCHEMBL17678061 | 0.69 | LMNA (0.66) | LMNAMAPTTSHRCREBBPHTT | |
| SCHEMBL17678352 | 0.69 | ALDH1A1 (0.51) | LMNAMAPTTSHRCREBBPSMN1; SMN2 | |
| SCHEMBL3839667 | 0.68 | KMT2A (0.42) | LMNATSHRSMN1; SMN2HSD17B10MEN1 | |
| SCHEMBL21026154 | 0.68 | LMNA (0.63) | LMNAMAPTTSHRCREBBPHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011099832-A2 | NOVEL BENZIMIDAZOLE COMPOUND, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CRYSTALGENOMICS, INC. (KR) | 2011-08-18 | — | — | WO | disclosed |