Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | SCD | O00767 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12727008 | 0.94 | CHRM1 (0.34) | F10CHRM1 | |
| SCHEMBL12461518 | 0.79 | F10 (0.35) | F10 | |
| SCHEMBL12460946 | 0.73 | F10 (0.31) | F10 | |
| SCHEMBL1715631 | 0.71 | ITGB3 (0.35) | F10 | |
| SCHEMBL24960558 | 0.67 | TSHR (0.34) | F10 | |
| SCHEMBL8171000 | 0.67 | SPHK1 (0.33) | SPHK2SPHK1 | |
| SCHEMBL19844032 | 0.64 | SPHK1 (0.38) | CHRM1SPHK1SCD | |
| SCHEMBL12461551 | 0.64 | — | — | |
| SCHEMBL11868944 | 0.63 | SCD (0.39) | CHRM1SPHK1THRBSCD | |
| SCHEMBL10665201 | 0.63 | EPHX2 (0.42) | SPHK2SPHK1THRATHRBSCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989450-B2 | Functionalized diarylisoxazoles inhibitors of ciclooxygenase | UNIVERSITA' DEGLI STUDI DI BARI (IT) | 2011-08-02 | — | — | US | disclosed |
| US-20090181970-A1 | Functionalized diarylisoxazoles inhibitors of ciclooxygenase | UNIVERSITA' DEGLI STUDI DI BARI (IT) | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181970-A1 | Functionalized diarylisoxazoles inhibitors of ciclooxygenase | PTGIS, ALOX5, ALOX15 | F10 1641/4885CHRM1 2471/4885SPHK2 3014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.