Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.41 |
| ▸ | GMNN | O75496 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | BLM | P54132 | 3/20 | 0.41 |
| ▸ | CETP | P11597 | 3/20 | 0.41 |
| ▸ | UBE2N | P61088 | 3/20 | 0.41 |
| ▸ | THPO | P40225 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 3/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23627333 | 1.00 | LMNA (0.41) | LMNACYP2D6MAPTSPHK1GMNN | |
| SCHEMBL22096924 | 0.98 | LMNA (0.38) | LMNACYP2D6MAPTSPHK1GMNN | |
| SCHEMBL23436516 | 0.98 | LMNA (0.42) | LMNACYP2D6MAPTSPHK1GMNN | |
| SCHEMBL23436525 | 0.82 | LMNA (0.42) | LMNACYP2D6MAPTSPHK1GMNN | |
| SCHEMBL2332834 | 0.81 | FDPS (0.36) | SPHK1FDPSSMPD1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4386616 | 0.79 | DNM1 (0.37) | SPHK1FDPSSMPD1MEN1KMT2A | |
| SCHEMBL16649028 | 0.79 | OPRM1 (0.37) | SPHK1FDPSSMPD1MEN1KMT2A | |
| SCHEMBL19274582 | 0.78 | OPRM1 (0.35) | SPHK1FDPSSMPD1THRBMAPK1 | |
| SCHEMBL23627348 | 0.78 | LMNA (0.40) | LMNACYP2D6MAPTSPHK1GMNN | |
| Water SCHEMBL7554274 | 0.78 | OPRM1 (0.43) | LMNACYP2D6MAPTSPHK1GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210205463-A1 | STABILITY-MODULATING LINKERS FOR USE WITH ANTIBODY DRUG CONJUGATES | PFIZER INC. (US) | 2021-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210205463-A1 | STABILITY-MODULATING LINKERS FOR USE WITH ANTIBODY DRUG CONJUGATES | FCGR2A, FCGRT, FCGR1A | LMNA 3839/4885CYP2D6 3416/4885MAPT 228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.