Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 6/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3065039 | 0.85 | CYP2C19 (0.40) | CYP2C19IDO1PTPRCCES2CES1 | |
| SCHEMBL22207429 | 0.85 | ALDH1A1 (0.48) | CYP2C19IDO1PTPRCCES2CES1 | |
| SCHEMBL27677975 | 0.80 | ALDH1A1 (0.44) | CYP2C19IDO1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL1722106 | 0.79 | CYP2C19 (0.47) | CYP2C19IDO1CES2CES1AKR1B1 | |
| SCHEMBL3068717 | 0.79 | CYP2C19 (0.38) | CYP2C19IDO1PTPRCCES2CES1 | |
| SCHEMBL3078052 | 0.79 | IDO1 (0.41) | CYP2C19IDO1PTPRCNOS3NOS1 | |
| SCHEMBL3078184 | 0.75 | CYP2C19 (0.38) | CYP2C19IDO1PTPRCCES2CES1 | |
| SCHEMBL3083549 | 0.74 | CYP2C19 (0.39) | CYP2C19IDO1PTPRCCES2CES1 | |
| Propionic Acid SCHEMBL29264558 | 0.74 | CYP2C19 (0.43) | CYP2C19IDO1PTPRCAKR1B1LMNA | |
| Dibenzyl Disulfide SCHEMBL28006296 | 0.74 | IDO1 (0.56) | CYP2C19IDO1PTPRCCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210214368-A1 | COMPOUNDS FOR THIOL-TRIGGERED COS AND/OR H2S RELEASE AND METHODS OF MAKING AND USING THE SAME | UNIVERSITY OF OREGON (US) | 2021-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210214368-A1 | COMPOUNDS FOR THIOL-TRIGGERED COS AND/OR H2S RELEASE AND METHODS OF MAKING AND USING THE SAME | CBS, TST, SQOR | CYP2C19 3864/4885IDO1 246/4885PTPRC 2818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.