Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3076761 | 0.84 | HPGD (0.41) | HPGDHSD17B10MAPTSMN1; SMN2MGLL | |
| SCHEMBL1318931 | 0.83 | HSD17B10 (0.44) | HPGDHSD17B10MAPTSMN1; SMN2MGLL | |
| SCHEMBL442435 | 0.76 | FFAR1 (0.43) | HPGDHSD17B10MAPTSMN1; SMN2MGLL | |
| SCHEMBL3086281 | 0.72 | HPGD (0.38) | HPGDHSD17B10MAPTSMN1; SMN2MGLL | |
| Ammonia Solution, Strong SCHEMBL14937632 | 0.71 | HPGD (0.92) | HPGDHSD17B10MAPTSMN1; SMN2MGLL | |
| Urea SCHEMBL27863158 | 0.70 | HPGD (0.67) | HPGDHSD17B10MAPTSMN1; SMN2MGLL | |
| SCHEMBL3085030 | 0.70 | HPGD (0.35) | HPGDHSD17B10MAPTSMN1; SMN2MGLL | |
| SCHEMBL3066664 | 0.70 | HPGD (0.44) | HPGDHSD17B10MAPTSMN1; SMN2MGLL | |
| SCHEMBL3059268 | 0.70 | HPGD (0.44) | HPGDHSD17B10MAPTSMN1; SMN2MGLL | |
| SCHEMBL3766616 | 0.69 | HPGD (0.55) | HPGDHSD17B10MAPTSMN1; SMN2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210214368-A1 | COMPOUNDS FOR THIOL-TRIGGERED COS AND/OR H2S RELEASE AND METHODS OF MAKING AND USING THE SAME | UNIVERSITY OF OREGON (US) | 2021-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210214368-A1 | COMPOUNDS FOR THIOL-TRIGGERED COS AND/OR H2S RELEASE AND METHODS OF MAKING AND USING THE SAME | CBS, TST, SQOR | HPGD 167/4885HSD17B10 2807/4885MAPT 4435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.