Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23631569 | 0.89 | NTSR1 (0.48) | ALDH1A1POLBKDM4EHPGDHSD17B10 | |
| SCHEMBL23631678 | 0.81 | ATM (0.50) | ALDH1A1POLBKDM4EHPGDHSD17B10 | |
| SCHEMBL23631589 | 0.75 | ALDH1A1 (0.47) | ALDH1A1POLBKDM4EHPGDHSD17B10 | |
| SCHEMBL23631612 | 0.75 | KMT2A (0.51) | ALDH1A1POLBKDM4EHPGDHSD17B10 | |
| SCHEMBL30839297 | 0.72 | HTR2C (0.42) | KDM4ESMN1; SMN2KMT2ACYP3A4CYP2C9 | |
| SCHEMBL29162311 | 0.72 | HTR2C (0.42) | KDM4ESMN1; SMN2KMT2ACYP3A4CYP2C9 | |
| SCHEMBL29162312 | 0.72 | HTR2C (0.42) | KDM4ESMN1; SMN2KMT2ACYP3A4CYP2C9 | |
| SCHEMBL30839311 | 0.72 | HTR2C (0.42) | KDM4ESMN1; SMN2KMT2ACYP3A4CYP2C9 | |
| SCHEMBL23956074 | 0.67 | HTR2C (0.40) | CYP3A4CYP2C9 | |
| SCHEMBL23956070 | 0.67 | HTR2C (0.40) | CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210214359-A1 | Compounds and Methods for Treating Bacterial Infections | UNIV NEW YORK (US) | 2021-07-15 | — | — | US | disclosed |
| US-20210214359-A1 | Compounds and Methods for Treating Bacterial Infections | UNIV NEW YORK (US) | 2021-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210214359-A1 | Compounds and Methods for Treating Bacterial Infections | CBS, MPO, QSOX1 | ALDH1A1 744/4885POLB 1658/4885KDM4E 2239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.