Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10916183 | 0.87 | ABCB1 (0.53) | ABCB1 | |
| Tonabersat SCHEMBL29717099 | 0.83 | ABCC9 (0.62) | ABCC9 | |
| Tonabersat SCHEMBL29377931 | 0.83 | ABCC9 (0.62) | ABCC9 | |
| Tonabersat SCHEMBL5917016 | 0.83 | ABCC9 (0.62) | ABCC9 | |
| Tonabersat SCHEMBL7169677 | 0.83 | ABCC9 (0.62) | ABCC9 | |
| Tonabersat SCHEMBL29373962 | 0.83 | ABCC9 (0.62) | ABCC9 | |
| Tonabersat SCHEMBL260661 | 0.83 | ABCC9 (0.62) | ABCC9 | |
| Tonabersat SCHEMBL7790566 | 0.78 | ABCC9 (0.46) | ABCC9 | |
| SCHEMBL7478768 | 0.77 | ABCB1 (0.47) | ABCB1ABCC9 | |
| SCHEMBL7478764 | 0.77 | ABCB1 (0.47) | ABCB1ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11058665-B2 | Methods for treating brain metastasis | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2021-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11058665-B2 | Methods for treating brain metastasis | GJA1, GJB2, EPCAM | ABCB1 395/4885ABCC9 439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.