SCHEMBL2363427

SCHEMBL2363427

CC(C)OCCC(=O)O[SiH3]

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
LMNA P02545 2/20 0.32
EPHX2 P34913 1/20 0.30
TSHR P16473 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7741371 0.79 LMNA (0.52) ALDH1A1LMNAEPHX2TSHR
SCHEMBL13502946 0.79 ALDH1A1 (0.40) ALDH1A1LMNAEPHX2TSHRL3MBTL1
SCHEMBL6651373 0.79 TSHR (0.55) ALDH1A1LMNATSHR
SCHEMBL5702363 0.76
SCHEMBL3823424 0.76 CYP1A2 (0.47) ALDH1A1LMNATSHRL3MBTL1
SCHEMBL10404752 0.74 DGKA (0.45) ALDH1A1LMNAL3MBTL1
SCHEMBL7056960 0.74 ALDH1A1 (0.37) ALDH1A1LMNA
SCHEMBL31379423 0.74 CYP2D6 (0.38) ALDH1A1LMNAEPHX2
Cyclopropane SCHEMBL27365076 0.74 TSHR (0.48) ALDH1A1LMNAEPHX2TSHR
Cyclopropane SCHEMBL27363746 0.74 LMNA (0.47) ALDH1A1LMNAEPHX2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1448714-B1 SYNTHESIS AND USE ALKYLALKOXYACYLOXYSILANES AND BLENDS THEREOF FOR USE AS A CROSSLINKING AGENT IN MOISTURE CURING RTV'S MOMENTIVE PERFORMANCE MAT INC (US) 2011-08-24 EP disclosed
EP-1448714-A4 SYNTHESIS AND USE ALKYLALKOXYACYLOXYSILANES AND BLENDS THEREOF FOR USE AS A CROSSLINKING AGENT IN MOISTURE CURING RTV'S GEN ELECTRIC (US) 2007-04-04 EP disclosed
EP-1448714-A1 SYNTHESIS AND USE ALKYLALKOXYACYLOXYSILANES AND BLENDS THEREOF FOR USE AS A CROSSLINKING AGENT IN MOISTURE CURING RTV'S General Electronic Company (US) 2004-08-25 EP disclosed
US-6737494-B2 POLYSILOXANE USING ORGANTIN POLYMERIZATION CALALYSTS GENERAL ELECTRIC COMPANY 2004-05-18 US disclosed
WO-2003042304-A1 SYNTHESIS AND USE OF ALKYLALKOXY ACYLOXYSILANES AND BLENDS THEREOF FOR USE AS A CROSSLINKING AGENT IN MOISTURE CURING RTV'S GENERAL ELECTRIC COMPANY (US) 2003-05-22 WO disclosed
US-20030092861-A1 Synthesis and use of alkylalkoxyacyloxysilanes and blends thereof for use as a crosslinking agent in moisture curing RTV'S GENERAL ELECTRIC COMPANY 2003-05-15 US disclosed