Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 18/20 | 0.72 |
| ▸ | CTSK | P43235 | 15/20 | 0.72 |
| ▸ | CTSL | P07711 | 2/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.53 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14952748 | 0.87 | CTSS (0.59) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL12712549 | 0.84 | CTSS (0.74) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL18884395 | 0.84 | CTSS (0.74) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL8239753 | 0.83 | CTSS (0.72) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL10076131 | 0.82 | CTSS (0.67) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL12980339 | 0.81 | CTSK (0.61) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL12980341 | 0.81 | CTSK (0.61) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL21111329 | 0.79 | CTSS (0.67) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL3275039 | 0.79 | CTSS (0.67) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL12336548 | 0.79 | CTSS (0.67) | CTSSCTSKCTSLCTSBCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8008007-B2 | S-adenosyl-L-methionine analogs with extended activated groups for transfer by methyltransferases | RWTH AACHEN (DE) | 2011-08-30 | — | — | US | disclosed |
| EP-1874790-B1 | NEW S-ADENOSYL-L-METHIONINE ANALOGS WITH EXTENDED ACTIVATED GROUPS FOR TRANSFER BY METHYLTRANSFERASES | RWTH AACHEN (DE) | 2010-08-18 | — | — | EP | disclosed |
| US-20090018101-A1 | S-ADENOSYL-L-METHIONINE ANALOGS WITH EXTENDED ACTIVATED GROUPS FOR TRANSFER BY METHYLTRANSFERASES | RWTH AACHEN (DE) | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018101-A1 | S-ADENOSYL-L-METHIONINE ANALOGS WITH EXTENDED ACTIVATED GROUPS FOR TRANSFER BY METHYLTRANSFERASES | BHMT2, MSRB3, PRMT3 | CTSS 3814/4885CTSK 4664/4885CTSL 4492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.