Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.37 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21889279 | 0.81 | AOC3 (0.40) | KDM4EPOLBCCNE2CCNE1CDK2 | |
| SCHEMBL23631838 | 0.75 | LMNA (0.44) | KDM4EALPLPOLBCYP1A2CYP2C9 | |
| SCHEMBL7263917 | 0.68 | HSD17B10 (0.42) | KDM4EALOX15APOBEC3AHSD17B10APOBEC3G | |
| SCHEMBL3299561 | 0.67 | POLB (0.62) | KDM4EALPLPOLBCYP1A2CYP2C9 | |
| SCHEMBL10806751 | 0.66 | CA2 (0.44) | KDM4ECYP1A2HSD17B10L3MBTL1RAB9A | |
| SCHEMBL11540720 | 0.66 | CCNE2 (0.48) | KDM4EPOLBCCNE2CCNE1CDK2 | |
| SCHEMBL15305663 | 0.65 | POLB (0.46) | KDM4EALPLPOLBCYP1A2CYP2C9 | |
| SCHEMBL6124859 | 0.65 | — | — | |
| SCHEMBL18141918 | 0.64 | APOBEC3A (0.54) | KDM4EPOLBCYP1A2CYP2C19ALOX15 | |
| SCHEMBL11294168 | 0.63 | NPC1 (0.47) | L3MBTL1RAB9ANPC1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11911372-B2 | Compounds | CTXT PTY LTD (AU) | 2024-02-27 | — | — | US | disclosed |
| US-20210213004-A1 | Compounds | CTXT PTY LTD (AU) | 2021-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210213004-A1 | Compounds | SLC10A1, ABCB11, REN | KDM4E 3932/4885ALPL 1275/4885POLB 4295/4885 |
| US-11911372-B2 | Compounds | SLC10A1, ABCB11, REN | KDM4E 3932/4885ALPL 1275/4885POLB 4295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.