SCHEMBL23635972

SCHEMBL23635972

C=NCc1ccc(OC)c(-c2cc(NS(=O)(=O)c3c(OC)cccc3OC)no2)c1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KAT7 O95251 17/20 0.41
KAT6A Q92794 17/20 0.41
KAT6B Q8WYB5 12/20 0.41
KAT5 Q92993 9/20 0.41
KAT8 Q9H7Z6 9/20 0.41
NR3C1 P04150 2/20 0.39
PGR P06401 2/20 0.39
LMNA P02545 1/20 0.39
TP53 P04637 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23631795 0.87 KAT7 (0.43) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL23635883 0.82 KDM4E (0.50) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL23631827 0.81 ALDH1A1 (0.51) LMNATP53MAPTHPGDNPSR1
SCHEMBL23631813 0.81 KMT2A (0.47) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL23635956 0.81 MAPT (0.47) KAT7KAT6ANR3C1PGRTP53
SCHEMBL23635850 0.81 NR3C1 (0.41) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL30842111 0.80 KAT7 (0.65) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL23635958 0.80 KAT7 (0.65) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL23292514 0.79 TSHR (0.46) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL23631841 0.78 RAB9A (0.46) KAT6ATP53MAPTHPGDNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210213004-A1 Compounds CTXT PTY LTD (AU) 2021-07-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210213004-A1 Compounds SLC10A1, ABCB11, REN KAT7 490/4885KAT6A 951/4885KAT6B 766/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.