SCHEMBL2363598

SCHEMBL2363598

C=CCNc1cccc(O)c1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.41
CA1 P00915 4/20 0.41
ALDH1A1 P00352 4/20 0.41
HPGD P15428 3/20 0.41
ADAMTS4 O75173 1/20 0.41
EGFR P00533 1/20 0.41
LMNA P02545 1/20 0.41
FYN P06241 1/20 0.41
MMP2 P08253 1/20 0.41
MMP9 P14780 1/20 0.41
ALOX15 P16050 1/20 0.41
MMP8 P22894 1/20 0.41
CA6 P23280 1/20 0.41
CDK2 P24941 1/20 0.41
MMP12 P39900 1/20 0.41
RECQL P46063 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ADAMTS5 Q9UNA0 1/20 0.41
RRM2 P31350 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL564626 0.85 GABRA1 (0.48) CA2CA1ALDH1A1HPGDLMNA
SCHEMBL796531 0.84 KMT2A (0.48) CA2CA1ALDH1A1HPGDLMNA
SCHEMBL7864943 0.81 IDO1 (0.47) CA2CA1ALDH1A1HPGDLMNA
SCHEMBL9273078 0.81 MAPT (0.45) CA2CA1ALDH1A1LMNAHSD17B10
SCHEMBL11071612 0.80 MEN1 (0.39) CA2CA1ALDH1A1HPGDRRM2
Hydrochloric Acid SCHEMBL7926386 0.80 IDO1 (0.46) CA2CA1ALDH1A1HPGDLMNA
SCHEMBL10915633 0.78 ACHE (0.36) CA2CA1ALDH1A1LMNAHSD17B10
SCHEMBL4270047 0.78 ALDH1A1 (0.50) ALDH1A1HPGDLMNAMMP2HSD17B10
SCHEMBL565971 0.78 CA2 (0.37) CA2CA1ALDH1A1HPGDLMNA
SCHEMBL4784858 0.77 ALDH1A1 (0.44) CA2CA1ALDH1A1HPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7989007-B2 Weight loss composition VINCENT JAMES ENTERPRISES, LLC (US) 2011-08-02 US disclosed
US-20090214680-A1 Weight Loss Composition INVIVO BEVERAGES LLC 2009-08-27 US disclosed
WO-2009006366-A2 WEIGHT LOSS COMPOSITION VINCENT JAMES ENTERPRISES, LLC (US) 2009-01-08 WO disclosed
EP-1469730-A2 METHODS AND COMPOSITIONS FOR TREATING PARKINSON'S DISEASE BIOGEN, INC. (US) 2004-10-27 EP disclosed
WO-2003037260-A2 METHODS AND COMPOSITIONS FOR TREATING PARKINSON'S DISEASE BIOGEN, INC. (US) 2003-05-08 WO disclosed
WO-2002094378-A2 INCREASED FUNCTIONAL ACTIVITY AND/OR EXPRESSION OF ABC TRANSPORTERS PROTECTS AGAINST THE LOSS OF DOPAMINE NEURONS ASSOCIATED WITH PARKINSON'S DISEASE ACTIVE PASS PHARMACEUTICALS, INC. (CA) 2002-11-28 WO disclosed