Sugi Predict

Sugi Predict / Compounds / SCHEMBL565971

SCHEMBL565971

SCHEMBL565971

C=CCNc1cccc(C(C)(C)c2cccc(NCC=C)c2O)c1O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA2 P00918 2/20 0.37
▸ ALDH1A1 P00352 5/20 0.34
▸ HPGD P15428 1/20 0.34
▸ RRM2 P31350 1/20 0.34
▸ KMT2A Q03164 3/20 0.33
▸ MEN1 O00255 2/20 0.33
▸ GABRA1 P14867 2/20 0.33
▸ GABRB2 P47870 2/20 0.33
▸ CA12 O43570 1/20 0.33
▸ CA1 P00915 1/20 0.33
▸ CA9 Q16790 1/20 0.33
▸ CA14 Q9ULX7 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ HIF1A Q16665 1/20 0.33
▸ L3MBTL1 Q9Y468 2/20 0.33
▸ LMNA P02545 2/20 0.33
▸ MITF O75030 1/20 0.33
▸ NSD2 O96028 1/20 0.33
▸ CASP3 P42574 1/20 0.33
▸ HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL565583 0.90 ALDH1A1 (0.40) CA2ALDH1A1RRM2KMT2AMEN1
SCHEMBL564626 0.78 GABRA1 (0.48) CA2ALDH1A1HPGDRRM2KMT2A
SCHEMBL2363598 0.78 CA2 (0.41) CA2ALDH1A1HPGDRRM2KMT2A
SCHEMBL565941 0.77 ALDH1A1 (0.36) CA2ALDH1A1HPGDKMT2AMEN1
Ether SCHEMBL566237 0.72 MAPT (0.41) ALDH1A1HPGDRRM2KMT2AMEN1
SCHEMBL9273078 0.71 MAPT (0.45) CA2ALDH1A1RRM2KMT2AMEN1
SCHEMBL11119930 0.71 GABRA1 (0.59) CA2ALDH1A1KMT2AMEN1GABRA1
SCHEMBL17865619 0.71 ALDH1A1 (0.37) CA2ALDH1A1HPGDRRM2KMT2A
SCHEMBL4270047 0.71 ALDH1A1 (0.50) ALDH1A1HPGDMAPTL3MBTL1LMNA
SCHEMBL565866 0.71 ESR1 (0.46) CA2ALDH1A1HPGDKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8674029-B2 Method of preparing stabilized polymeric systems using polymeric peroxides Sunocs LLC (US) 2014-03-18 — — US disclosed
US-20120035307-A1 PROCESS FOR MAKING STABLIZED POLYMERIC SYSTEMS WITH NANOSTRUCTURES SONG CHENGQIAN (US) 2012-02-09 — — US disclosed
US-20120035315-A1 METHOD OF PREPARING STABLIZED POLYMERIC SYSTEMS USING POLYMERIC PEROXIDES SONG CHENGQIAN (US) 2012-02-09 — — US disclosed
US-7498467-B2 Antioxidant and bisaminophenol derivative IDEMITSU KOSAN CO., LTD. (JP) 2009-03-03 — — US disclosed
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN CO., LTD. (JP) 2008-07-03 — — US disclosed
US-20060208227-A1 Antioxidant and bisaminophenol derivative IDEMITSU LOSAN CO., LTD (JP) 2006-09-21 — — US disclosed
EP-1612254-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN COMPANY LIMITED (JP) 2006-01-04 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE CBR1, CBR3, HMOX1 CA2 1653/4885ALDH1A1 204/4885HPGD 208/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.