Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 7/20 | 0.51 |
| ▸ | RORC | P51449 | 11/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21619941 | 0.86 | RORC (0.52) | RORCHDAC8HDAC6 | |
| SCHEMBL23636631 | 0.86 | RORC (0.50) | RORCMAPK14 | |
| SCHEMBL23636632 | 0.86 | RORC (0.50) | RORCMAPK14 | |
| SCHEMBL23636940 | 0.84 | RORC (0.49) | RORCMAPK14 | |
| SCHEMBL23636926 | 0.84 | RORC (0.49) | RORCMAPK14 | |
| SCHEMBL28600987 | 0.84 | MCHR1 (0.48) | MCHR1RORCHDAC8HDAC6 | |
| SCHEMBL30065059 | 0.84 | MCHR1 (0.48) | MCHR1RORCHDAC8HDAC6 | |
| SCHEMBL23636960 | 0.84 | MCHR1 (0.48) | MCHR1RORCHDAC8HDAC6 | |
| SCHEMBL23632655 | 0.83 | RORC (0.52) | RORCMAPK14 | |
| SCHEMBL23636819 | 0.83 | RORC (0.52) | RORCMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021139599-A1 | RORγT INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 东莞市东阳光新药研发有限公司 | 2021-07-15 | — | — | WO | disclosed |