Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 3/20 | 0.40 |
| ▸ | HRH2 | P25021 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
| ▸ | BCR | P11274 | 2/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.35 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2363548 | 0.88 | KDM4E (0.43) | LTA4HTEAD1TEAD3 | |
| SCHEMBL2364770 | 0.88 | GPR119 (0.41) | ACKR3LTA4HHRH2HRH1GPR119 | |
| SCHEMBL2365258 | 0.87 | ACKR3 (0.42) | ACKR3LTA4HPPARDPPARAABL1 | |
| SCHEMBL2365504 | 0.87 | ACKR3 (0.42) | ACKR3LTA4HPPARDPPARAABL1 | |
| SCHEMBL2365577 | 0.86 | HRH2 (0.37) | ACKR3LTA4HHRH2HRH1TEAD1 | |
| SCHEMBL2365569 | 0.81 | KCNA5 (0.36) | ACKR3LTA4HHRH2HRH1PPARD | |
| SCHEMBL2365495 | 0.77 | GRIN2B (0.47) | ACKR3LTA4HHRH2HRH1ABL1 | |
| SCHEMBL2365541 | 0.76 | GAA (0.39) | — | |
| SCHEMBL2363554 | 0.73 | HTR7 (0.36) | LTA4H | |
| SCHEMBL2365327 | 0.71 | KDM4E (0.40) | LTA4HFFAR1TEAD1TEAD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011089550-A1 | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI AVENTIS (FR) | 2011-07-28 | — | — | WO | claimed |
| WO-2011089550-A1 | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI AVENTIS (FR) | 2011-07-28 | — | — | WO | disclosed |