SCHEMBL2364087

SCHEMBL2364087

CCC(F)C(F)(F)[Sn](OCc1ccccc1)(OCc1ccccc1)C(F)(F)C(F)CC

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36
TRPA1 O75762 1/20 0.35
IDO1 P14902 1/20 0.34
ALDH1A1 P00352 2/20 0.33
TP53 P04637 1/20 0.33
AGXT P21549 1/20 0.33
CA1 P00915 1/20 0.33
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
NR1H2 P55055 1/20 0.32
NR1H3 Q13133 1/20 0.32
SYK P43405 1/20 0.32
TACR1 P25103 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4544269 0.94 TSHR (0.34) TSHRTRPA1IDO1ALDH1A1TP53
SCHEMBL2328694 0.75 TSHR (0.35) TSHRTRPA1IDO1ALDH1A1TP53
SCHEMBL2345113 0.73 TSHR (0.33) TSHRTRPA1IDO1ALDH1A1TP53
SCHEMBL2322381 0.72
SCHEMBL29403866 0.69 CHRM3 (0.40) TSHRALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL2322367 0.69 TSHR (0.39) TSHRIDO1ALDH1A1AGXTCA1
SCHEMBL2328701 0.69 TSHR (0.43) TSHRIDO1AGXTCA1MAPT
SCHEMBL2327784 0.69 TSHR (0.35) TSHRTRPA1IDO1ALDH1A1AGXT
SCHEMBL2322981 0.69
SCHEMBL2325249 0.68 TSHR (0.38) TSHRIDO1ALDH1A1AGXTCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1987881-B1 METHOD FOR SEPARATION AND COLLECTION OF DIALKYL TIN DIALKOXIDE ASAHI KASEI CHEMICALS CORP (JP) 2011-08-17 EP disclosed
US-7842828-B2 Method for separating out and recovering dialkyltin dialkoxide ASAHI KASEI CHEMICALS CORPORATION (JP) 2010-11-30 US disclosed
US-20100160662-A1 Method for Separating Out and Recovering Dialkyltin Dialkoxide ASAHI KASEI KABUSHIKI KAISHA (JP) 2010-06-24 US disclosed
EP-1987881-A1 METHOD FOR SEPARATION AND COLLECTION OF DIALKYL TIN DIALKOXIDE Asahi Kasei Chemicals Corporation (JP) 2008-11-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100160662-A1 Method for Separating Out and Recovering Dialkyltin Dialkoxide ALOX5, ALOX15B, ALOX15 TSHR 3272/4885TRPA1 716/4885IDO1 2152/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.