Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 7/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2238850 | 0.83 | P2RX7 (0.59) | P2RX7TBXA2RGRM4ALDH1A1CHRM2 | |
| SCHEMBL2364024 | 0.81 | CYP1A2 (0.55) | CYP1A2CYP2C9CYP2C19ALDH1A1KDM4E | |
| SCHEMBL2364113 | 0.80 | LONP1 (0.46) | KDM4EHPGDSMN1; SMN2LMNA | |
| SCHEMBL2364022 | 0.75 | KDM4E (0.41) | GRM4FPR2GRM5KDM4ELMNA | |
| SCHEMBL12999512 | 0.73 | P2RX7 (0.60) | P2RX7TBXA2RGRM4CYP1A2CYP2C9 | |
| SCHEMBL7034276 | 0.73 | P2RX7 (0.52) | P2RX7GRM4 | |
| SCHEMBL7034270 | 0.73 | P2RX7 (0.52) | P2RX7GRM4 | |
| SCHEMBL2364158 | 0.72 | HSPA9 (0.42) | ALDH1A1GRM5 | |
| SCHEMBL107554 | 0.71 | P2RX7 (1.00) | P2RX7GRM4CYP1A2CYP2C19FAAH | |
| SCHEMBL31627592 | 0.71 | P2RX7 (1.00) | P2RX7GRM4CYP1A2CYP2C19FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011095218-A1 | TEMPLATE-FIXED PEP TIDOMIME TICS WITH CXCR7 MODULATING ACTIVITY | POLYPHOR AG (CH) | 2011-08-11 | — | — | WO | disclosed |