Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA9 | P38646 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 7/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2237622 | 0.83 | HSPA9 (0.46) | HSPA9PLA2G4ACES1HDAC3HDAC1 | |
| SCHEMBL2364398 | 0.75 | HPGD (0.54) | HDAC1ALDH1A1 | |
| SCHEMBL2631739 | 0.73 | HDAC1 (0.60) | TBXAS1PLA2G4ACES1HDAC3HDAC1 | |
| SCHEMBL2364024 | 0.73 | CYP1A2 (0.55) | ALDH1A1 | |
| SCHEMBL2364022 | 0.73 | KDM4E (0.41) | HDAC3HDAC1GRM5 | |
| SCHEMBL2364113 | 0.73 | LONP1 (0.46) | — | |
| SCHEMBL2364467 | 0.72 | P2RX7 (0.54) | ALDH1A1GRM5 | |
| SCHEMBL2335604 | 0.72 | GABRA5 (0.40) | HDAC3HDAC1ALDH1A1 | |
| SCHEMBL1769145 | 0.71 | GRIN3B (0.48) | HSPA9ALDH1A1 | |
| SCHEMBL1769143 | 0.71 | GRIN3B (0.48) | HSPA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011095218-A1 | TEMPLATE-FIXED PEP TIDOMIME TICS WITH CXCR7 MODULATING ACTIVITY | POLYPHOR AG (CH) | 2011-08-11 | — | — | WO | disclosed |