Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LONP1 | P36776 | 13/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PSMB11 | A5LHX3 | 6/20 | 0.44 |
| ▸ | PSMA7 | O14818 | 6/20 | 0.44 |
| ▸ | PSMB1 | P20618 | 6/20 | 0.44 |
| ▸ | PSMA1 | P25786 | 6/20 | 0.44 |
| ▸ | PSMA2 | P25787 | 6/20 | 0.44 |
| ▸ | PSMA3 | P25788 | 6/20 | 0.44 |
| ▸ | PSMA4 | P25789 | 6/20 | 0.44 |
| ▸ | PSMB8 | P28062 | 6/20 | 0.44 |
| ▸ | PSMB9 | P28065 | 6/20 | 0.44 |
| ▸ | PSMA5 | P28066 | 6/20 | 0.44 |
| ▸ | PSMB4 | P28070 | 6/20 | 0.44 |
| ▸ | PSMB6 | P28072 | 6/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 6/20 | 0.44 |
| ▸ | PSMB10 | P40306 | 6/20 | 0.44 |
| ▸ | PSMB3 | P49720 | 6/20 | 0.44 |
| ▸ | PSMB2 | P49721 | 6/20 | 0.44 |
| ▸ | PSMA6 | P60900 | 6/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2240079 | 0.83 | KMT2A (0.48) | LONP1LMNAHPGDPSMB11PSMA7 | |
| SCHEMBL2364467 | 0.80 | P2RX7 (0.54) | LMNAHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL2364022 | 0.78 | KDM4E (0.41) | LMNAKDM4E | |
| SCHEMBL2364024 | 0.76 | CYP1A2 (0.55) | KMT2AKDM4EHTT | |
| SCHEMBL31325642 | 0.76 | LONP1 (0.49) | LONP1LMNAHPGDPSMB11PSMA7 | |
| SCHEMBL31285763 | 0.76 | KDM4E (0.67) | LMNAHPGDKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL2335604 | 0.75 | GABRA5 (0.40) | LMNAHPGDKMT2AHTT | |
| SCHEMBL5656679 | 0.73 | KDM4E (0.72) | LMNAHPGDKMT2AKDM4ESMN1; SMN2 | |
| Pyrazinamide SCHEMBL28149190 | 0.73 | ADORA3 (0.72) | SMYD3KMT2AKDM4ESMN1; SMN2NAPRT | |
| SCHEMBL25286303 | 0.73 | LONP1 (0.49) | LONP1LMNAHPGDPSMB11PSMA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011095218-A1 | TEMPLATE-FIXED PEP TIDOMIME TICS WITH CXCR7 MODULATING ACTIVITY | POLYPHOR AG (CH) | 2011-08-11 | — | — | WO | disclosed |