Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21810833 | 0.90 | GAA (0.40) | GAAKMT2ASMN1; SMN2RIPK1POLB | |
| SCHEMBL23645420 | 0.82 | L3MBTL1 (0.41) | GAAKMT2ASMN1; SMN2POLBMAPT | |
| SCHEMBL23645360 | 0.82 | FAAH (0.36) | GAAKMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL23645323 | 0.79 | ATM (0.38) | GAAKMT2APOLBMAPTALDH1A1 | |
| SCHEMBL23653209 | 0.79 | LMNA (0.39) | RIPK1LMNA | |
| SCHEMBL23645339 | 0.75 | FAAH (0.34) | GAAKMT2AMAPTFAAHJMJD6 | |
| SCHEMBL19299941 | 0.75 | KMT2A (0.41) | GAAKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL23645362 | 0.75 | KMT2A (0.39) | GAAKMT2APOLBALDH1A1FAAH | |
| SCHEMBL23645403 | 0.73 | ALDH1A1 (0.40) | GAAKMT2ASMN1; SMN2POLBMAPT | |
| SCHEMBL23645416 | 0.73 | RIPK1 (0.44) | GAAKMT2ASMN1; SMN2RIPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112689636-B | Novel heteroatom aromatic amide derivative and pharmaceutical agent containing same | 科研制药株式会社 | 2024-08-20 | — | — | CN | disclosed |
| EP-3851436-A1 | NOVEL HETEROAROMATIC AMIDE DERIVATIVE AND MEDICINE CONTAINING SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 2021-07-21 | — | — | EP | disclosed |