Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.46 |
| ▸ | CTSG | P08311 | 5/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 5/20 | 0.46 |
| ▸ | CMA1 | P23946 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12471939 | 0.77 | PRSS1 (0.49) | POLBPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL3658399 | 0.75 | ITGB3 (0.53) | POLBRAB9ALMNASMN1; SMN2NPC1 | |
| SCHEMBL28194649 | 0.75 | NAAA (0.58) | POLBRAB9AHPGDLMNAKDM4E | |
| SCHEMBL3848857 | 0.74 | SMN1; SMN2 (0.63) | POLBRAB9AHPGDLMNAKDM4E | |
| SCHEMBL27530408 | 0.73 | POLB (0.66) | POLBRAB9AHPGDKDM4ENAAA | |
| SCHEMBL10440896 | 0.73 | POLB (0.48) | POLBRAB9AHPGDLMNAKDM4E | |
| Pivalate SCHEMBL10779199 | 0.73 | LMNA (0.67) | POLBRAB9AHPGDLMNASMN1; SMN2 | |
| SCHEMBL7887426 | 0.72 | PRSS1 (0.53) | PRSS1CTSGCTRB1CMA1RAB9A | |
| SCHEMBL290981 | 0.72 | TDP1 (0.50) | POLBRAB9AHPGDLMNASMN1; SMN2 | |
| SCHEMBL2364751 | 0.72 | RAB9A (0.49) | RAB9AHPGDLMNANAAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | claimed |
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |