Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | TET3 | O43151 | 2/20 | 0.51 |
| ▸ | FBXL19 | Q6PCT2 | 2/20 | 0.51 |
| ▸ | CXXC5 | Q7LFL8 | 2/20 | 0.51 |
| ▸ | TET1 | Q8NFU7 | 2/20 | 0.51 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.51 |
| ▸ | CXXC4 | Q9H2H0 | 2/20 | 0.51 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23381801 | 0.84 | KMT2A (0.44) | KMT2ATET3FBXL19CXXC5TET1 | |
| SCHEMBL16874836 | 0.83 | OPRM1 (0.59) | KMT2ATET3FBXL19CXXC5TET1 | |
| SCHEMBL23647376 | 0.82 | KMT2A (0.59) | KMT2ATET3FBXL19CXXC5TET1 | |
| SCHEMBL13908097 | 0.82 | BACE1 (0.55) | KMT2ATET3FBXL19CXXC5TET1 | |
| SCHEMBL10322683 | 0.80 | OPRM1 (0.47) | KMT2ATET3FBXL19CXXC5TET1 | |
| SCHEMBL4662764 | 0.80 | CA12 (0.43) | SMN1; SMN2ALDH1A1HPGDOPRM1OPRD1 | |
| SCHEMBL1581919 | 0.79 | OPRM1 (0.56) | KMT2ATET3FBXL19CXXC5TET1 | |
| SCHEMBL23647460 | 0.78 | ALDH1A1 (0.54) | KMT2ATET3FBXL19CXXC5TET1 | |
| SCHEMBL16874714 | 0.78 | HSD11B1 (0.56) | KMT2ATET3FBXL19CXXC5TET1 | |
| SCHEMBL895814 | 0.78 | MAOB (0.52) | CYP3A4ALDH1A1MAPK1MAPTOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021143680-A1 | HETEROARYL DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江海正药业股份有限公司 | 2021-07-22 | — | — | WO | disclosed |