Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | TET3 | O43151 | 2/20 | 0.59 |
| ▸ | FBXL19 | Q6PCT2 | 2/20 | 0.59 |
| ▸ | CXXC5 | Q7LFL8 | 2/20 | 0.59 |
| ▸ | TET1 | Q8NFU7 | 2/20 | 0.59 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.59 |
| ▸ | CXXC4 | Q9H2H0 | 2/20 | 0.59 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TACR2 | P21452 | 4/20 | 0.49 |
| ▸ | TACR1 | P25103 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1480336 | 0.85 | LMNA (0.55) | KMT2ATET3FBXL19CXXC5TET1 | |
| SCHEMBL23660780 | 0.83 | BACE1 (0.53) | KMT2ATET3FBXL19CXXC5TET1 | |
| SCHEMBL23647557 | 0.82 | KMT2A (0.51) | KMT2ATET3FBXL19CXXC5TET1 | |
| SCHEMBL10002472 | 0.82 | LMNA (0.60) | KMT2ATET3FBXL19CXXC5TET1 | |
| SCHEMBL5205623 | 0.82 | LMNA (0.65) | KMT2ATET3FBXL19CXXC5TET1 | |
| SCHEMBL16874836 | 0.81 | OPRM1 (0.59) | KMT2ATET3FBXL19CXXC5TET1 | |
| SCHEMBL2112323 | 0.80 | LMNA (0.68) | KMT2ACYP3A4CYP2C19LMNACHRM1 | |
| SCHEMBL23647652 | 0.80 | NNMT (0.43) | KMT2ATET3FBXL19CXXC5TET1 | |
| SCHEMBL23647525 | 0.78 | HSD11B1 (0.40) | KMT2ATET3FBXL19CXXC5TET1 | |
| SCHEMBL2701584 | 0.78 | ALDH1A1 (0.59) | KMT2ACYP3A4CYP2C19LMNAHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021143680-A1 | HETEROARYL DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江海正药业股份有限公司 | 2021-07-22 | — | — | WO | disclosed |