Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | TLR2 | O60603 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 5/20 | 0.32 |
| ▸ | DRD2 | P14416 | 5/20 | 0.32 |
| ▸ | DRD3 | P35462 | 3/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | NT5E | P21589 | 1/20 | 0.30 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23651247 | 0.86 | NT5E (0.39) | OPRM1TLR2DRD4DRD2DRD3 | |
| SCHEMBL31398727 | 0.86 | NT5E (0.39) | OPRM1TLR2DRD4DRD2DRD3 | |
| SCHEMBL18526322 | 0.81 | NT5E (0.41) | OPRM1TLR2DRD4DRD2DRD3 | |
| SCHEMBL24942516 | 0.79 | OPRM1 (0.37) | OPRM1TLR2DRD4DRD2DRD3 | |
| SCHEMBL23917997 | 0.78 | NT5E (0.33) | NT5E | |
| SCHEMBL18526237 | 0.77 | OPRM1 (0.35) | OPRM1TLR2DRD4DRD2DRD3 | |
| SCHEMBL18493212 | 0.77 | OPRM1 (0.34) | OPRM1TLR2USP2ALDH1A1SMN1; SMN2 | |
| SCHEMBL30112567 | 0.75 | NT5E (0.40) | OPRM1SMN1; SMN2NT5EF10CYP3A4 | |
| SCHEMBL24942508 | 0.75 | NT5E (0.40) | OPRM1SMN1; SMN2NT5EF10CYP3A4 | |
| SCHEMBL31398730 | 0.74 | ALDH1A1 (0.34) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11067566-B2 | Photochromic xanthene fluorophores and their utility live-cell beyond the diffraction limit | HOWARD HUGHES MEDICAL INSTITUTE (US) | 2021-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11067566-B2 | Photochromic xanthene fluorophores and their utility live-cell beyond the diffraction limit | XPA, ANXA5, KIF20A | OPRM1 4866/4885TLR2 1481/4885DRD4 2207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.