Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 2/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ITPR3 | Q14573 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31398727 | 1.00 | NT5E (0.39) | NT5EOPRM1RORCTTRALDH1A1 | |
| SCHEMBL18526322 | 0.96 | NT5E (0.41) | NT5EOPRM1RORCTTRALDH1A1 | |
| SCHEMBL23917997 | 0.91 | NT5E (0.33) | NT5ETTRKCNH2 | |
| SCHEMBL18526325 | 0.88 | NT5E (0.40) | NT5EOPRM1RORCTTRALDH1A1 | |
| SCHEMBL30112567 | 0.87 | NT5E (0.40) | NT5EOPRM1RORCTTRSMN1; SMN2 | |
| SCHEMBL24942508 | 0.87 | NT5E (0.40) | NT5EOPRM1RORCTTRSMN1; SMN2 | |
| SCHEMBL18526372 | 0.86 | OPRM1 (0.37) | NT5EOPRM1ALDH1A1SMN1; SMN2USP2 | |
| SCHEMBL23651268 | 0.86 | OPRM1 (0.35) | NT5EOPRM1ALDH1A1SMN1; SMN2USP2 | |
| SCHEMBL24942980 | 0.85 | NT5E (0.39) | NT5EOPRM1RORCTTRALDH1A1 | |
| SCHEMBL30112650 | 0.85 | NT5E (0.39) | NT5EOPRM1RORCTTRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210318293-A1 | Photochromic xanthene fluorophores and their utility in live-cell imaging beyond the diffraction limit | HOWARD HUGHES MEDICAL INSTITUTE (US) | 2021-10-14 | — | — | US | disclosed |
| US-11067566-B2 | Photochromic xanthene fluorophores and their utility live-cell beyond the diffraction limit | HOWARD HUGHES MEDICAL INSTITUTE (US) | 2021-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11067566-B2 | Photochromic xanthene fluorophores and their utility live-cell beyond the diffraction limit | XPA, ANXA5, KIF20A | NT5E 1453/4885OPRM1 4866/4885RORC 3731/4885 |
| US-20210318293-A1 | Photochromic xanthene fluorophores and their utility in live-cell imaging beyond the diffraction limit | XPA, KIF20A, KIF20B | NT5E 1651/4885OPRM1 4875/4885RORC 3872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.