Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23651247 | 0.91 | NT5E (0.39) | NT5EKCNH2TTR | |
| SCHEMBL31398727 | 0.91 | NT5E (0.39) | NT5EKCNH2TTR | |
| SCHEMBL18526322 | 0.87 | NT5E (0.41) | NT5EKCNH2TTR | |
| SCHEMBL24942998 | 0.79 | OPRK1 (0.35) | KCNH2TTR | |
| SCHEMBL30112718 | 0.79 | OPRK1 (0.35) | KCNH2TTR | |
| SCHEMBL18526325 | 0.79 | NT5E (0.40) | NT5EKCNH2TTR | |
| SCHEMBL24942508 | 0.79 | NT5E (0.40) | NT5EKCNH2TTR | |
| SCHEMBL30112567 | 0.79 | NT5E (0.40) | NT5EKCNH2TTR | |
| SCHEMBL30112828 | 0.78 | GSTP1 (0.37) | KCNH2 | |
| SCHEMBL23651268 | 0.78 | OPRM1 (0.35) | NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210318293-A1 | Photochromic xanthene fluorophores and their utility in live-cell imaging beyond the diffraction limit | HOWARD HUGHES MEDICAL INSTITUTE (US) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210318293-A1 | Photochromic xanthene fluorophores and their utility in live-cell imaging beyond the diffraction limit | XPA, KIF20A, KIF20B | NT5E 1651/4885KCNH2 2807/4885TTR 4737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.