Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 4/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 5/20 | 0.33 |
| ▸ | NAMPT | P43490 | 2/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.31 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2178905 | 0.77 | GCK (0.38) | GCKNAMPT | |
| SCHEMBL2179681 | 0.75 | GCK (0.48) | GCKSCN9AKCNH2SCN5A | |
| SCHEMBL3761810 | 0.70 | GCK (0.53) | GCK | |
| SCHEMBL2178177 | 0.70 | GCK (0.47) | GCK | |
| SCHEMBL2178179 | 0.65 | ALDH1A1 (0.34) | GCKNAMPTALDH1A1 | |
| SCHEMBL2177869 | 0.64 | GCK (0.44) | GCK | |
| SCHEMBL2178624 | 0.63 | GCK (0.38) | GCK | |
| SCHEMBL2197573 | 0.61 | PIK3CA (0.34) | GCKKCNH2ALDH1A1 | |
| SCHEMBL1810013 | 0.61 | PTK2 (0.57) | NAMPTPTK2ALDH1A1 | |
| SCHEMBL2179805 | 0.61 | CNR2 (0.38) | GCKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011080755-A1 | FUSED NITROGEN HETEROCYCLIC COMPOUNDS, PROCESS OF PREPARATION AND USES THEREOF | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-07-07 | — | — | WO | claimed |