Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 3/20 | 0.34 |
| ▸ | GCK | P35557 | 4/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2179805 | 0.91 | CNR2 (0.38) | PIK3CAGCKLRRK2ATRALDH1A1 | |
| SCHEMBL2178524 | 0.70 | GCK (0.42) | GCKLRRK2 | |
| SCHEMBL12490119 | 0.69 | GCK (0.46) | GCKALDH1A1PTGS2PTGS1 | |
| SCHEMBL2178905 | 0.66 | GCK (0.38) | GCK | |
| SCHEMBL2178527 | 0.65 | GCK (0.35) | GCKLRRK2ATRPTGS2PTGS1 | |
| SCHEMBL1256644 | 0.60 | SMN1; SMN2 (0.59) | ALDH1A1BLMEGFR | |
| SCHEMBL29977958 | 0.60 | SMN1; SMN2 (0.59) | ALDH1A1BLMEGFR | |
| SCHEMBL6808653 | 0.59 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL4689890 | 0.58 | SMN1; SMN2 (0.48) | ALDH1A1 | |
| SCHEMBL602439 | 0.57 | HCAR1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011080755-A1 | FUSED NITROGEN HETEROCYCLIC COMPOUNDS, PROCESS OF PREPARATION AND USES THEREOF | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-07-07 | — | — | WO | claimed |
| WO-2011080755-A1 | FUSED NITROGEN HETEROCYCLIC COMPOUNDS, PROCESS OF PREPARATION AND USES THEREOF | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-07-07 | — | — | WO | disclosed |