Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 4/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.38 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2365494 | 0.88 | ACKR3 (0.45) | LTA4HTEAD1TEAD3 | |
| SCHEMBL2365577 | 0.87 | HRH2 (0.37) | SMN1; SMN2LTA4HTEAD1TEAD3 | |
| SCHEMBL2364770 | 0.87 | GPR119 (0.41) | LTA4HTEAD1TEAD3 | |
| SCHEMBL2365327 | 0.83 | KDM4E (0.40) | KDM4EALDH1A1LMNAHTTNPC1 | |
| SCHEMBL2365569 | 0.80 | KCNA5 (0.36) | LTA4HTEAD1TEAD3 | |
| SCHEMBL2363549 | 0.79 | GRIN2B (0.58) | NPC1RAB9ASMN1; SMN2CHRM4GRIN2B | |
| SCHEMBL2365541 | 0.79 | GAA (0.39) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2365504 | 0.76 | ACKR3 (0.42) | LTA4HTEAD1TEAD3 | |
| SCHEMBL2365258 | 0.76 | ACKR3 (0.42) | LTA4HEPHX2TEAD1TEAD3 | |
| SCHEMBL2363554 | 0.76 | HTR7 (0.36) | KDM4EALDH1A1LMNALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011089550-A1 | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI AVENTIS (FR) | 2011-07-28 | — | — | WO | claimed |
| WO-2011089550-A1 | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI AVENTIS (FR) | 2011-07-28 | — | — | WO | disclosed |