Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 8/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | F13A1 | P00488 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TGM1 | P22735 | 1/20 | 0.43 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31228347 | 0.90 | TGM2 (0.65) | TGM2PTPN1PTPN11BTKF13A1 | |
| SCHEMBL613090 | 0.90 | TGM2 (0.65) | TGM2PTPN1PTPN11BTKF13A1 | |
| SCHEMBL2761954 | 0.82 | TGM2 (0.62) | TGM2PTPN1PTPN11F13A1LMNA | |
| SCHEMBL17524758 | 0.81 | TGM2 (0.55) | TGM2PTPN1PTPN11BTKF13A1 | |
| SCHEMBL29416535 | 0.81 | TGM2 (0.55) | TGM2PTPN1PTPN11 | |
| SCHEMBL2316517 | 0.81 | TGM2 (0.55) | TGM2PTPN1PTPN11 | |
| SCHEMBL15938830 | 0.80 | TGM2 (0.50) | TGM2PTPN1PTPN11BTKF13A1 | |
| Hydrochloric Acid SCHEMBL29278808 | 0.79 | TGM2 (0.53) | TGM2PTPN1PTPN11 | |
| SCHEMBL7417077 | 0.79 | GAA (0.57) | LMNAKDM4EMAPTALDH1A1RECQL | |
| SCHEMBL9357321 | 0.78 | TGM2 (0.57) | TGM2PTPN1PTPN11BTKF13A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968337-B1 | HETEROARYL COMPOUNDS AND USES THEREOF | CELGENE CAR LLC (BM) | 2021-07-21 | — | — | EP | disclosed |