Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 3/20 | 0.42 |
| ▸ | LSS | P48449 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29824343 | 0.81 | HTR5A (0.52) | HTR5AKMT2AMEN1HTR6 | |
| SCHEMBL23648897 | 0.81 | HTR5A (0.52) | HTR5AKMT2AMEN1HTR6 | |
| SCHEMBL23657359 | 0.79 | SLC6A4 (0.58) | HTR5AHTR6HTR2A | |
| SCHEMBL23657403 | 0.78 | HRH3 (0.54) | LSSKDM4EALDH1A1HRH3SMN1; SMN2 | |
| SCHEMBL23657406 | 0.76 | HTR2A (0.50) | KMT2AMEN1LSSHTR2AALDH1A1 | |
| SCHEMBL23657177 | 0.75 | SLC6A4 (0.55) | HTR5AHTR6HTR2A | |
| SCHEMBL23657212 | 0.75 | HRH3 (0.55) | LSSKDM4EALDH1A1HRH3SMN1; SMN2 | |
| SCHEMBL12850609 | 0.71 | HTR2A (0.65) | HTR6HTR2A | |
| SCHEMBL23657195 | 0.70 | MTNR1A (0.47) | — | |
| SCHEMBL23657351 | 0.69 | HTR1A (0.53) | KMT2AMEN1HTR6HTR2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021145729-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION (KR) | 2021-07-22 | — | — | WO | disclosed |