Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.74 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.74 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.74 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 9/20 | 0.61 |
| ▸ | RAB9A | P51151 | 8/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.61 |
| ▸ | TP53 | P04637 | 7/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.61 |
| ▸ | RELA | Q04206 | 2/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL823173 | 0.84 | KMT2A (0.84) | CHRNB2CHRNB4CHRNA3CHRNA4MAPT | |
| SCHEMBL3362301 | 0.82 | CHRNB2 (0.64) | CHRNB2CHRNB4CHRNA3CHRNA4MAPT | |
| SCHEMBL14097068 | 0.81 | LCK (0.66) | CHRNB2CHRNB4CHRNA3CHRNA4MAPT | |
| SCHEMBL8660822 | 0.81 | CHRNB2 (0.63) | CHRNB2CHRNB4CHRNA3CHRNA4MAPT | |
| SCHEMBL16675189 | 0.81 | KMT2A (0.73) | MAPTMEN1KMT2AKDM4ERECQL | |
| SCHEMBL4710453 | 0.80 | SMN1; SMN2 (0.69) | CHRNB2CHRNB4CHRNA3CHRNA4MAPT | |
| SCHEMBL13988385 | 0.78 | CHRNB2 (0.56) | CHRNB2CHRNB4CHRNA3CHRNA4MAPT | |
| SCHEMBL821802 | 0.77 | KMT2A (0.70) | CHRNB2CHRNB4CHRNA3CHRNA4MAPT | |
| SCHEMBL12549321 | 0.77 | LCK (0.60) | CHRNB2CHRNB4CHRNA3CHRNA4MAPT | |
| SCHEMBL2632145 | 0.77 | ADORA3 (0.74) | MAPTMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210220408-A1 | ARYL HYDROCARBON RECEPTOR ANTAGONISTS AND METHODS OF USE | EDIGENE BIOTECHNOLOGY, INC. (CN) | 2021-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210220408-A1 | ARYL HYDROCARBON RECEPTOR ANTAGONISTS AND METHODS OF USE | AHR, ARNT, ARSA | CHRNB2 1904/4885CHRNB4 2440/4885CHRNA3 2039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.