Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.62 |
| ▸ | NPC1 | O15118 | 8/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.57 |
| ▸ | AGER | Q15109 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3879405 | 0.87 | TRPV1 (0.60) | HDAC2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28835090 | 0.80 | AGER (0.58) | RAB9ANPC1SMN1; SMN2HDAC2HDAC3 | |
| SCHEMBL17066707 | 0.79 | RAB9A (0.88) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL15214314 | 0.79 | RAB9A (0.88) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL25970267 | 0.79 | RAB9A (0.88) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL25491824 | 0.79 | RAB9A (0.88) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL558643 | 0.79 | PDPK1 (0.63) | RAB9ANPC1SMN1; SMN2HDAC2HDAC3 | |
| Water SCHEMBL20550178 | 0.77 | ADRB2 (0.62) | RAB9ANPC1SMN1; SMN2HDAC2HDAC3 | |
| SCHEMBL12310125 | 0.77 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2HDAC1HDAC6 | |
| SCHEMBL822378 | 0.77 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210220408-A1 | ARYL HYDROCARBON RECEPTOR ANTAGONISTS AND METHODS OF USE | EDIGENE BIOTECHNOLOGY, INC. (CN) | 2021-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210220408-A1 | ARYL HYDROCARBON RECEPTOR ANTAGONISTS AND METHODS OF USE | AHR, ARNT, ARSA | RAB9A 4056/4885NPC1 1022/4885SMN1; SMN2 3198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.