Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 13/20 | 1.00 |
| ▸ | NPC1 | O15118 | 12/20 | 1.00 |
| ▸ | PKM | P14618 | 9/20 | 1.00 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | GRM5 | P41594 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.50 |
| ▸ | TP53 | P04637 | 10/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24681052 | 0.84 | RAB9A (0.73) | RAB9ANPC1PKMNR1H4GRM5 | |
| SCHEMBL10353034 | 0.76 | RAB9A (0.60) | RAB9ANPC1PKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL5959908 | 0.76 | RAB9A (0.72) | RAB9ANPC1PKMNR1H4SMN1; SMN2 | |
| SCHEMBL4551922 | 0.74 | CASP3 (0.66) | RAB9ANPC1PKMGRM5HPGD | |
| SCHEMBL29661988 | 0.71 | NPC1 (0.55) | RAB9ANPC1PKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL1423031 | 0.71 | CHRNB2 (0.71) | RAB9ANPC1PKMSMN1; SMN2TP53 | |
| SCHEMBL6780851 | 0.71 | S1PR1 (0.55) | RAB9ANPC1PKMNR1H4SMN1; SMN2 | |
| SCHEMBL28637707 | 0.70 | NR1H4 (0.78) | RAB9ANPC1NR1H4SMN1; SMN2TP53 | |
| SCHEMBL28651531 | 0.70 | NR1H4 (0.78) | RAB9ANPC1NR1H4SMN1; SMN2TP53 | |
| SCHEMBL9965991 | 0.70 | NPC1 (0.54) | RAB9ANPC1PKMGRM5SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210220408-A1 | ARYL HYDROCARBON RECEPTOR ANTAGONISTS AND METHODS OF USE | EDIGENE BIOTECHNOLOGY, INC. (CN) | 2021-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210220408-A1 | ARYL HYDROCARBON RECEPTOR ANTAGONISTS AND METHODS OF USE | AHR, ARNT, ARSA | RAB9A 4056/4885NPC1 1022/4885PKM 3827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.