Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 4/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24581135 | 0.86 | LMNA (0.32) | LMNA | |
| SCHEMBL23162797 | 0.78 | HSD11B1 (0.48) | HSD11B1PTGS2LMNAHTR6 | |
| SCHEMBL23665021 | 0.76 | PTGS2 (0.39) | HSD11B1PTGS2LMNAHTR6PDK2 | |
| SCHEMBL18790124 | 0.73 | HTR2C (0.46) | HTR6PDK2PDK4 | |
| SCHEMBL25464003 | 0.72 | SLC6A4 (0.37) | LMNAHTR6PDK2PDK4 | |
| SCHEMBL19628517 | 0.72 | SLC6A4 (0.36) | HTR6PDK2PDK4 | |
| SCHEMBL10180103 | 0.72 | PTGS2 (0.55) | HSD11B1PTGS2LMNAHTR6ALOX5AP | |
| SCHEMBL24603708 | 0.72 | CNR2 (0.37) | HSD11B1ALOX5APFEN1 | |
| SCHEMBL15035936 | 0.72 | HSD11B1 (0.41) | HSD11B1 | |
| SCHEMBL23664866 | 0.71 | PTGS2 (0.44) | PTGS2LMNAHTR6ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021143693-A1 | ARYL OR HETEROARYL PYRIDONE OR PYRIMIDINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF | 苏州泽璟生物制药股份有限公司 | 2021-07-22 | — | — | WO | disclosed |