Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | FABP3 | P05413 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23664869 | 0.81 | SLC9A1 (0.36) | SLC9A1LMNAHSP90AA1HTTHRH4 | |
| SCHEMBL12695017 | 0.73 | ALDH1A1 (0.47) | LMNAHSP90AA1HTTPTGS2ALDH1A1 | |
| SCHEMBL15077045 | 0.73 | HTT (0.51) | LMNAHTTHRH4PTGS2ALDH1A1 | |
| SCHEMBL26091408 | 0.73 | ENPP2 (0.39) | LMNAPTGS2ALDH1A1GAA | |
| SCHEMBL23664867 | 0.72 | LMNA (0.40) | LMNAHSP90AA1HRH4PTGS2ALDH1A1 | |
| SCHEMBL26812067 | 0.68 | LMNA (0.43) | SLC9A1LMNAHSP90AA1HRH4PTGS2 | |
| SCHEMBL15041660 | 0.68 | LMNA (0.39) | LMNAPTGS2ALDH1A1GAAL3MBTL1 | |
| SCHEMBL1368631 | 0.68 | AKR1C3 (0.39) | SLC9A1LMNAHSP90AA1HRH4PTGS2 | |
| SCHEMBL18541985 | 0.67 | TTR (0.41) | LMNAHTTALDH1A1HPGDGAA | |
| SCHEMBL12248188 | 0.67 | AKR1C3 (0.41) | LMNAPTGS2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022135591-A1 | ARYL OR HETEROARYL PYRIDONE OR PYRIMIDONE DERIVATIVE AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 苏州泽璟生物制药股份有限公司 | 2022-06-30 | — | — | WO | disclosed |
| WO-2021249563-A1 | ARYL OR HETEROARYL PYRIDONE OR PYRIMIDONE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 苏州泽璟生物制药股份有限公司 | 2021-12-16 | — | — | WO | disclosed |
| WO-2021143693-A1 | ARYL OR HETEROARYL PYRIDONE OR PYRIMIDINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF | 苏州泽璟生物制药股份有限公司 | 2021-07-22 | — | — | WO | disclosed |