Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | S100B | P04271 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29442599 | 0.81 | S100B (0.61) | APAF1ALDH1A1TDP1CYP3A4ALOX15 | |
| SCHEMBL33872 | 0.81 | S100B (0.61) | APAF1ALDH1A1TDP1CYP3A4ALOX15 | |
| SCHEMBL31361979 | 0.80 | ALDH1A1 (0.52) | APAF1ALDH1A1TDP1CYP3A4ALOX15 | |
| SCHEMBL2313495 | 0.80 | ALDH1A1 (0.52) | APAF1ALDH1A1TDP1CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL9293613 | 0.79 | S100B (0.59) | APAF1ALDH1A1TDP1CYP3A4ALOX15 | |
| SCHEMBL15928738 | 0.79 | S100B (0.48) | APAF1ALDH1A1TDP1CASP1CYP3A4 | |
| SCHEMBL6739605 | 0.77 | ALDH1A1 (0.70) | APAF1ALDH1A1TDP1CASP1CYP3A4 | |
| SCHEMBL346399 | 0.77 | ALDH1A1 (0.53) | APAF1ALDH1A1TDP1CYP3A4ALOX15 | |
| SCHEMBL8371365 | 0.76 | ALDH1A1 (0.46) | APAF1ALDH1A1TDP1CASP1CYP3A4 | |
| SCHEMBL538824 | 0.76 | S100B (0.71) | ALDH1A1TDP1CASP1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9827228-B2 | Opioid receptor modulators and use thereof | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2017-11-28 | — | — | US | disclosed |
| EP-2651899-B1 | SUBSTITUTED 6,6-FUSED NITROGENOUS HETEROCYCLIC COMPOUNDS AND USES THEREOF | HOFFMANN LA ROCHE (CH) | 2017-05-31 | — | — | EP | disclosed |
| US-20170056377-A1 | OPIOID RECEPTOR MODULATORS AND USE THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-03-02 | — | — | US | disclosed |
| US-9220671-B2 | Dye composition comprising at least four dye precursors including at least one oxidation base and at least one coupler | L'OREAL (FR) | 2015-12-29 | — | — | US | disclosed |
| WO-2014118092-A2 | DYE COMPOSITION COMPRISING AT LEAST ONE PARTICULAR LIPOPHILIC META-PHENYLENEDIAMINE COUPLER IN A MEDIUM RICH IN FATTY SUBSTANCES, PROCESSES AND DEVICES | L'OREAL (FR) | 2014-08-07 | — | — | WO | disclosed |
| EP-2366004-A1 | LUBRICATING COMPOSITION CONTAINING A POLYMER FUNCTIONALISED WITH A CARBOXYLIC ACID AND AN AROMATIC POLYAMINE | The Lubrizol Corporation (US) | 2011-09-21 | — | — | EP | disclosed |
| US-7670753-B2 | Lithographic printing plate precursor | EASTMAN KODAK COMPANY (US) | 2010-03-02 | — | — | US | disclosed |
| US-20080261146-A1 | Lithographic Printing Plate Precursor | EASTMAN KODAK COMPANY | 2008-10-23 | — | — | US | disclosed |
| EP-1782127-B1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR | EASTMAN KODAK CO (US) | 2008-04-02 | — | — | EP | disclosed |
| EP-1782127-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR | EASTMAN KODAK COMPANY (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006023667-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR | EASTMAN KODAK COMPANY (US) | 2006-03-02 | — | — | WO | disclosed |
| CN-1318776-A | Development composition and thermosensitive recording material | MITSUI CHEMICALS INC (JP) | 2001-10-24 | — | — | CN | disclosed |
| EP-0217247-B1 | PROCESS FOR THE PREPARATION OF POLYAMINES, POLYAMINES AND THEIR USE IN THE PREPARATION OF POLYURETHANES | BAYER AG (DE) | 1991-03-13 | — | — | EP | disclosed |
| US-4931595-A | Catalytic hydrolysis process for polyamines | BAYER AKTIENGESELLSCHAFT (DE) | 1990-06-05 | — | — | US | disclosed |
| EP-0217247-A2 | Process for the preparation of polyamines, polyamines and their use in the preparation of polyurethanes | BAYER AG (DE) | 1987-04-08 | — | — | EP | disclosed |
| US-4289880-A | BLUE COLOR ON POLYACRYLONITRILE | CIBA-GEIGY CORPORATION (US) | 1981-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170056377-A1 | OPIOID RECEPTOR MODULATORS AND USE THEREOF | OPRM1, OPRK1, OPRL1 | APAF1 4634/4885ALDH1A1 1408/4885TDP1 4694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.